Mitochondria are unique cellular organelles in having a DNA of their own. This mitochondrial DNA is known as mtDNA. In nearly all mammals the mitochondrial DNA is exclusively inherited from the mother and fathers also occasionally contribute to the inheritance. mt DNA mutations accumulate during human life and may contribute a wide range of pathologies. Thus understanding how mt DNA is inherited has wide implications across medicine.
This open textbook attempts to unravel the basic concepts about mitochondrial DNA ,its inheritance and mitochondrial genetic disorders . The book also features with interactive exercises
This topic will be part of curriculum for most Undergraduate and Post graduate programmes in Life Sciences.
India, Chennai, Tamil Nadu
Contributed by: Malathi V (Twitter: @dr_malathiveera)